完成机构：[1]College of Marine Life Science, Ocean University of China, Qingdao 266003, China [2]Shandong Academy of Food and Fermentation Industries, Jinan 250013, China [3]Graduate School of Biotechnology, Korea University, Seoul 136-701, Korea [4]Depantment of Pharmacy, Weifang Medical University, Weifang 261042, China